Many other studies have compared Adderall or Vyvanse to placebo (an inactive pill) or to other medications used for ADHD and confirmed that both Adderall and Vyvanse improve various symptoms of ADHD. It took about two hours for Adderall to start working and three hours for Vyvanse, and the effects of each drug lasted for approximately 16 hours.
#Amphetamine salts trial
Similar results were reported in a trial of 18 adults with ADHD. Both were well tolerated and no significant differences were noted in their side effects. One study did look at the effect both drugs had on classroom-based behavior in a group of children with ADHD, and reported that both seemed equally effective at improving attention-span, rule following and interactions with peers and adults. Unfortunately, researchers have not really looked into how effective Adderall is compared to Vyvanse, and vice-versa. 1 Are there any studies that directly compare Adderall to Vyvanse? By blocking their re-uptake, levels of these neurotransmitters between nerves are increased, which helps relieve symptoms of inattention and agitation in children and adults with ADHD. These neurotransmitters are called norepinephrine and dopamine. 2īecause Adderall and Vyvanse both contain amphetamines they work in a similar way, and that is by blocking the re-uptake of two neurotransmitters (chemical substances that help nerves talk to each other) in the body. Once lisdexamfetamine is inside the body it gets converted into dextroamphetamine (its active form) as soon as it touches red blood cells. Vyvanse is the brand name for lisdexamfetamine. It's easier to call these mixed amphetamine salts, or MAS for short. See also: Compare Tool - Adderall vs Vyvanse What is in Adderall and Vyvanse?Īdderall is a brand name for a combination drug that contains four different types of amphetamines (dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate). The risk of dependence (this means how likely you are to become dependent or addicted to the drug) appears similar for both Adderall and Vyvanse. Studies have shown that Vyvanse is just as effective as Adderall, and side effects are similar. One disadvantage of Vyvanse is that there is no generic form available, which makes it more costly than Adderall.īecause both drugs contain amphetamines, they work in a similar way. One advantage of Vyvanse is that it may be less likely to be abused however, there are no head-to-head trials that compare the abuse potential of Vyvanse to Adderall. The four amphetamine salts that Adderall contains are dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate. Lisdexamfetamine gets converted into dexamphetamine once it is in the body. You should use caution while operating vehicles and hazardous machinery, especially if you're beginning to take this medication.The main difference between Adderall and Vyvanse is that Adderall is a mixture of four different kinds of amphetamine salts while Vyvanse only contains one type of amphetamine salt, called lisdexamfetamine.
If you or your child has Tourette's syndrome, Adderall XR could worsen motor and vocal tics. These medications are associated with disrupted circulation to the extremities (called peripheral vasculopathy) and with Raynaud's phenomenon, which involves decreased blood flow to certain areas of the body, like the fingers or toes. Stimulants may cause blood circulation problems.Blurred vision may occur with this type of medication. Stimulant treatment can disrupt vision.If seizures are present, Adderall XR shouldn't be taken.
Stimulants may increase the likelihood of a seizure for people with a prior history of them, with established electroencephalogram (EEG) abnormalities, or, very rarely, for people without a history of this condition.
Stimulant use may impact growth in children.
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